Sympathetic refers to the sympathetic nervous system (SNS), which is one of the two main branches of the autonomic nervous system (ANS). The other branch is the parasympathetic nervous system. The sympathetic nervous system is responsible for the body’s “fight or flight” response, preparing the body to handle stressful or emergency situations. Here’s a detailed overview of the sympathetic nervous system:

  1. Core Functions:
    • Fight or Flight Response: The sympathetic nervous system activates the body’s acute stress response, preparing it to either fight or flee from perceived threats. This response is crucial for survival in dangerous or high-stress situations.
    • Energy Mobilization: It helps mobilize energy resources and increase alertness, ensuring that the body is ready to respond quickly and effectively.
  2. Anatomy and Pathways:
    • Thoracolumbar Origin: The sympathetic nervous system originates from the thoracic and lumbar regions of the spinal cord (T1 to L2). It is composed of a network of sympathetic ganglia (clusters of nerve cell bodies) located along the spinal cord.
    • Nerve Pathways: Sympathetic nerves travel from the spinal cord to various organs and tissues throughout the body, primarily using norepinephrine (noradrenaline) as a neurotransmitter to transmit signals.
  3. Physiological Effects:
    • Heart Rate: The sympathetic nervous system increases heart rate and the force of heart contractions to pump more blood and oxygen to vital organs and muscles.
    • Respiration: It stimulates the respiratory system to increase breathing rate and depth, enhancing oxygen intake.
    • Pupils: It causes dilation of the pupils (mydriasis) to allow more light into the eyes, improving vision in low-light conditions and enhancing awareness of surroundings.
    • Digestive Processes: It inhibits digestive functions by decreasing peristalsis and reducing the secretion of digestive enzymes, redirecting blood flow away from the digestive system to the muscles.
    • Sweating: It stimulates sweat production to help regulate body temperature and prepare the body for physical exertion.
  4. Balance with Parasympathetic Nervous System:
    • Opposing Actions: The sympathetic and parasympathetic nervous systems work in tandem to maintain balance in the body. While the sympathetic nervous system is activated during stress or emergencies, the parasympathetic nervous system helps to calm the body and restore normal functions once the stressor is removed.
  5. Clinical Relevance:
    • Stress and Health: Chronic activation of the sympathetic nervous system due to prolonged stress or anxiety can lead to various health issues, including hypertension, cardiovascular disease, digestive disorders, and immune system suppression.
    • Sympathetic Nervous System Disorders: Conditions related to sympathetic nervous system dysfunction include certain types of hypertension, panic disorders, and conditions related to excessive sympathetic activation.
  6. Activation and Management:
    • Acute Stress: The sympathetic nervous system is activated during acute stress responses, such as in response to danger or high-pressure situations.
    • Chronic Stress Management: Techniques such as relaxation exercises, mindfulness, and stress management strategies can help mitigate the effects of chronic sympathetic activation and promote overall well-being.

Overall, the sympathetic nervous system plays a crucial role in preparing the body to handle stressful situations by activating the “fight or flight” response. By increasing alertness and mobilizing resources, it ensures that the body is ready to respond to challenges. Maintaining a balance between the sympathetic and parasympathetic nervous systems is essential for overall health and stress management.